Background: Tuberculosis (TB) remains a major public health issue in Ethiopia, with a high burden of both pulmonary and extrapulmonary TB cases. The prevalence of TB, including drug-resistant forms, continues to pose challenges, particularly in hospital settings like Dessie Comprehensive Specialized Hospital where both new and relapse cases are reported. This study aimed to determine the five-year prevalence and associated factors of MTB among TB-suspected cases at Dessie Comprehensive Specialized Hospital from 2020–2024. Method: A retrospective cross-sectional study was conducted using medical records of 1,850 TB-suspected cases. Data on socio-demographics, clinical presentation, and laboratory results (Gene-Xpert MTB/RIF) were analyzed using descriptive statistics and logistic regression. Results: The overall MTB prevalence was 23.4% (433/1,850). Significant risk factors included HIV co-infection (AOR=3.12, 95% CI: 2.34-4.16), malnutrition (AOR=2.45, 95% CI: 1.89-3.18), smoking (AOR=1.89, 95% CI: 1.32-2.71), and previous TB treatment (AOR=2.67, 95% CI: 1.95-3.65). Conclusion: The high MTB prevalence underscores the need for enhanced TB screening, particularly among high-risk groups.
| Published in | American Journal of Medical Science and Technology (Volume 1, Issue 1) |
| DOI | 10.11648/j.ajmst.20250101.14 |
| Page(s) | 18-31 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Tuberculosis, Mycobacterium Tuberculosis, Prevalence, Risk Factors, Ethiopia, Retrospective Study, HIV, Gene x Pert, Northeast, Ethiopia
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APA Style
Ali, I. E., Awol, L. S., Mohammed, M., Mohammed, K. S. (2025). A Five-Year Retrospective Study on the Prevalence and Associated Factors of Mycobacterium Tuberculosis Among Tuberculosis Suspected Cases at Dessie Comprehensive Specialized Hospital, Dessie, Ethiopia. American Journal of Medical Science and Technology, 1(1), 18-31. https://doi.org/10.11648/j.ajmst.20250101.14
ACS Style
Ali, I. E.; Awol, L. S.; Mohammed, M.; Mohammed, K. S. A Five-Year Retrospective Study on the Prevalence and Associated Factors of Mycobacterium Tuberculosis Among Tuberculosis Suspected Cases at Dessie Comprehensive Specialized Hospital, Dessie, Ethiopia. Am. J. Med. Sci. Technol. 2025, 1(1), 18-31. doi: 10.11648/j.ajmst.20250101.14
AMA Style
Ali IE, Awol LS, Mohammed M, Mohammed KS. A Five-Year Retrospective Study on the Prevalence and Associated Factors of Mycobacterium Tuberculosis Among Tuberculosis Suspected Cases at Dessie Comprehensive Specialized Hospital, Dessie, Ethiopia. Am J Med Sci Technol. 2025;1(1):18-31. doi: 10.11648/j.ajmst.20250101.14
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Download@article{10.11648/j.ajmst.20250101.14,
author = {Ismail Ebrie Ali and Lubaba Seid Awol and Mekonnen Mohammed and Kewser Seid Mohammed},
title = {A Five-Year Retrospective Study on the Prevalence and Associated Factors of Mycobacterium Tuberculosis Among Tuberculosis Suspected Cases at Dessie Comprehensive Specialized Hospital, Dessie, Ethiopia},
journal = {American Journal of Medical Science and Technology},
volume = {1},
number = {1},
pages = {18-31},
doi = {10.11648/j.ajmst.20250101.14},
url = {https://doi.org/10.11648/j.ajmst.20250101.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajmst.20250101.14},
abstract = {Background: Tuberculosis (TB) remains a major public health issue in Ethiopia, with a high burden of both pulmonary and extrapulmonary TB cases. The prevalence of TB, including drug-resistant forms, continues to pose challenges, particularly in hospital settings like Dessie Comprehensive Specialized Hospital where both new and relapse cases are reported. This study aimed to determine the five-year prevalence and associated factors of MTB among TB-suspected cases at Dessie Comprehensive Specialized Hospital from 2020–2024. Method: A retrospective cross-sectional study was conducted using medical records of 1,850 TB-suspected cases. Data on socio-demographics, clinical presentation, and laboratory results (Gene-Xpert MTB/RIF) were analyzed using descriptive statistics and logistic regression. Results: The overall MTB prevalence was 23.4% (433/1,850). Significant risk factors included HIV co-infection (AOR=3.12, 95% CI: 2.34-4.16), malnutrition (AOR=2.45, 95% CI: 1.89-3.18), smoking (AOR=1.89, 95% CI: 1.32-2.71), and previous TB treatment (AOR=2.67, 95% CI: 1.95-3.65). Conclusion: The high MTB prevalence underscores the need for enhanced TB screening, particularly among high-risk groups.},
year = {2025}
}
TY - JOUR T1 - A Five-Year Retrospective Study on the Prevalence and Associated Factors of Mycobacterium Tuberculosis Among Tuberculosis Suspected Cases at Dessie Comprehensive Specialized Hospital, Dessie, Ethiopia AU - Ismail Ebrie Ali AU - Lubaba Seid Awol AU - Mekonnen Mohammed AU - Kewser Seid Mohammed Y1 - 2025/12/26 PY - 2025 N1 - https://doi.org/10.11648/j.ajmst.20250101.14 DO - 10.11648/j.ajmst.20250101.14 T2 - American Journal of Medical Science and Technology JF - American Journal of Medical Science and Technology JO - American Journal of Medical Science and Technology SP - 18 EP - 31 PB - Science Publishing Group UR - https://doi.org/10.11648/j.ajmst.20250101.14 AB - Background: Tuberculosis (TB) remains a major public health issue in Ethiopia, with a high burden of both pulmonary and extrapulmonary TB cases. The prevalence of TB, including drug-resistant forms, continues to pose challenges, particularly in hospital settings like Dessie Comprehensive Specialized Hospital where both new and relapse cases are reported. This study aimed to determine the five-year prevalence and associated factors of MTB among TB-suspected cases at Dessie Comprehensive Specialized Hospital from 2020–2024. Method: A retrospective cross-sectional study was conducted using medical records of 1,850 TB-suspected cases. Data on socio-demographics, clinical presentation, and laboratory results (Gene-Xpert MTB/RIF) were analyzed using descriptive statistics and logistic regression. Results: The overall MTB prevalence was 23.4% (433/1,850). Significant risk factors included HIV co-infection (AOR=3.12, 95% CI: 2.34-4.16), malnutrition (AOR=2.45, 95% CI: 1.89-3.18), smoking (AOR=1.89, 95% CI: 1.32-2.71), and previous TB treatment (AOR=2.67, 95% CI: 1.95-3.65). Conclusion: The high MTB prevalence underscores the need for enhanced TB screening, particularly among high-risk groups. VL - 1 IS - 1 ER -
Department of Medical Laboratory, College of Dessie Health Science College, Dessie, Ethiopia
Department of Medical Laboratory, College of Dessie Health Science College, Dessie, Ethiopia
Department of Medical Laboratory, College of Dessie Health Science College, Dessie, Ethiopia
Department of Medical Laboratory, College of Dessie Health Science College, Dessie, Ethiopia
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