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Contemporary Definitions of Hypoglycemia as Frequent and Dangerous Syndrome and Coma

Received: 27 September 2019     Accepted: 17 October 2019     Published: 29 October 2019
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Abstract

A decrease in blood glucose is a frequent and dangerous violation of the most important part of homeostasis - energy. The high frequency of hypoglycemia is explained by a pathogenetic relationship with many diseases and syndromes, as well as the important role of hypoglycemia as a physiological regulator of energy metabolism. The danger of hypoglycemia is that glucose is actually the only source of energy for nerve structures and a lack of glucose could lead to their damage. In addition, deep hypoglycemia and low glucose concentration in brain cells could lead to cerebral edema. Analyzes of the respectful literature for a 20-year period, as well as my own clinical experience, including the work as an endocrinologist surgeon. The article presents the definitions of hypoglycemia, the typology of the syndrome in terms of causes, development mechanisms and clinical forms, also issues of the clinic and laboratory diagnostics are defined. Algorithms for the treatment of hypoglycemic coma and pathogenetic diagnosis of the main variants of hypoglycemia are proposed. Hypoglycemic syndrome [HS] and hypoglycemic coma [HC] are frequent clinical and laboratory paroxysms, especially among patients with diabetes mellitus. These conditions are of great danger to the health and even to the lives of patients, and require quick, qualified help.

Published in American Journal of Life Sciences (Volume 7, Issue 5)
DOI 10.11648/j.ajls.20190705.11
Page(s) 83-90
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Hypoglycemia, Glycopenia, Hypoglycemic Coma, Urgent Endocrinopathies

References
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[4] Yager J., Young R. Non-hypoglycemia is an epidemic condition. // New Engl. J. Med. - 1974. - № 14. - Р. 507-508.
[5] Inzucchi S., Kinder B. Endocrine Emergencies: Hypoglycemic and Hyperglycemic Crises. In: Textbook of Endocrine Surgery. (Eds. O. Ciark, Q-Y. Duh.). / WE Sounders Company. Washington etc.: - 1997. - Р. 175-181.
[6] Boyle P. J. Hypoglycemia. In: Medical Management of Diabetes Mellitus (transl. from English). By J. Leaty etc. (Eds). Marcel Dekker Inc. NY, Basel. 2000. Ch. 31.
[7] Ostroumova O. D., Akimova ES, Kochetkov A. I., Pereverzev A. P. Drug-induced hypoglycemia: a focus on drugs not belonging to the group of sugar-lowering drugs. // CONSILIUM Medicum. 2019. - T. 21. - No. 4. - P. 59-65. (in Rus.).
[8] Foster D., Rubinstein A. Hypoglycemia, insulinoma and other hormone-active tumors of the pancreas. In the book: Internal Diseases (transl. from English). ed. E. Braunwald and others M.: - Medicine. - 1997. - T. 9. - P. 232-247. (in Rus.).
[9] Kuzin N. M., Egorova L. V., Lakreeva MG. Gurevich L. E. Organic hyperinsulinism. // Clinical medicine. - 1998.- No. 4. - P. 7-11. (in Rus.).
[10] Rostomyan L. G., Rozhinskaya L. Ya., Tyulpakov A. N. Clinical and genetic characteristics of the syndrome of multiple endocrine neoplasia type 1 and the principles of its treatment. // Farmtek. - 2010. - No. 3. - P. 50-56. (in Rus.).
[11] Shustov S. B., Halimov U. Sh., Saluhov V. V., Trufanov G. E. Functional and Topical Diagnostic in Endocrinology. M.: GEOTAR Media. 2017. (in Rus.).
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  • APA Style

    Vyacheslav Semionovish Lukyanchikov. (2019). Contemporary Definitions of Hypoglycemia as Frequent and Dangerous Syndrome and Coma. American Journal of Life Sciences, 7(5), 83-90. https://doi.org/10.11648/j.ajls.20190705.11

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    ACS Style

    Vyacheslav Semionovish Lukyanchikov. Contemporary Definitions of Hypoglycemia as Frequent and Dangerous Syndrome and Coma. Am. J. Life Sci. 2019, 7(5), 83-90. doi: 10.11648/j.ajls.20190705.11

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    AMA Style

    Vyacheslav Semionovish Lukyanchikov. Contemporary Definitions of Hypoglycemia as Frequent and Dangerous Syndrome and Coma. Am J Life Sci. 2019;7(5):83-90. doi: 10.11648/j.ajls.20190705.11

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  • @article{10.11648/j.ajls.20190705.11,
      author = {Vyacheslav Semionovish Lukyanchikov},
      title = {Contemporary Definitions of Hypoglycemia as Frequent and Dangerous Syndrome and Coma},
      journal = {American Journal of Life Sciences},
      volume = {7},
      number = {5},
      pages = {83-90},
      doi = {10.11648/j.ajls.20190705.11},
      url = {https://doi.org/10.11648/j.ajls.20190705.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20190705.11},
      abstract = {A decrease in blood glucose is a frequent and dangerous violation of the most important part of homeostasis - energy. The high frequency of hypoglycemia is explained by a pathogenetic relationship with many diseases and syndromes, as well as the important role of hypoglycemia as a physiological regulator of energy metabolism. The danger of hypoglycemia is that glucose is actually the only source of energy for nerve structures and a lack of glucose could lead to their damage. In addition, deep hypoglycemia and low glucose concentration in brain cells could lead to cerebral edema. Analyzes of the respectful literature for a 20-year period, as well as my own clinical experience, including the work as an endocrinologist surgeon. The article presents the definitions of hypoglycemia, the typology of the syndrome in terms of causes, development mechanisms and clinical forms, also issues of the clinic and laboratory diagnostics are defined. Algorithms for the treatment of hypoglycemic coma and pathogenetic diagnosis of the main variants of hypoglycemia are proposed. Hypoglycemic syndrome [HS] and hypoglycemic coma [HC] are frequent clinical and laboratory paroxysms, especially among patients with diabetes mellitus. These conditions are of great danger to the health and even to the lives of patients, and require quick, qualified help.},
     year = {2019}
    }
    

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    AU  - Vyacheslav Semionovish Lukyanchikov
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    T2  - American Journal of Life Sciences
    JF  - American Journal of Life Sciences
    JO  - American Journal of Life Sciences
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    AB  - A decrease in blood glucose is a frequent and dangerous violation of the most important part of homeostasis - energy. The high frequency of hypoglycemia is explained by a pathogenetic relationship with many diseases and syndromes, as well as the important role of hypoglycemia as a physiological regulator of energy metabolism. The danger of hypoglycemia is that glucose is actually the only source of energy for nerve structures and a lack of glucose could lead to their damage. In addition, deep hypoglycemia and low glucose concentration in brain cells could lead to cerebral edema. Analyzes of the respectful literature for a 20-year period, as well as my own clinical experience, including the work as an endocrinologist surgeon. The article presents the definitions of hypoglycemia, the typology of the syndrome in terms of causes, development mechanisms and clinical forms, also issues of the clinic and laboratory diagnostics are defined. Algorithms for the treatment of hypoglycemic coma and pathogenetic diagnosis of the main variants of hypoglycemia are proposed. Hypoglycemic syndrome [HS] and hypoglycemic coma [HC] are frequent clinical and laboratory paroxysms, especially among patients with diabetes mellitus. These conditions are of great danger to the health and even to the lives of patients, and require quick, qualified help.
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Author Information
  • Medical Centre "Medstyle-Effect", Moscow, Russia

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