MDS are clonal disorders of multipotent or myeloid stem cells. The disease is characterized by inefficient hematopoiesis responsible for peripheral cytopenias and contrasting with a rich marrow. The natural course of this disease is acute myeloid leukemia (AML). This is a retrospective study on the files of patients who had a haematological assessment at the laboratory of the military hospital Avicenna Marrakech between July 2014 and July 2018 for a duration of 4 years. Included in our study were all patients with documented myelodysplasia. The average age of patients is 63.63 years with extremes of 19 years and 89 years; the sex ratio was 1.3 (17 men and 13 women). NFS was abnormal in all patients, 96.66% of whom had anemia. The myelogram was performed in all patients and allowed the diagnosis of MDS in 90% of cases. Our study shows that management needs to be further improved by selecting high-risk MDS patients, potentially candidates for allogeneic hematopoietic stem cell transplantation.
| Published in | American Journal of Laboratory Medicine (Volume 4, Issue 6) |
| DOI | 10.11648/j.ajlm.20190406.16 |
| Page(s) | 115-118 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Myelodysplasia, Haemogram, Anemia, Thrombocytopenia, Neutropenia-Myelogram, Genetic Mutation
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APA Style
Mouhib Hanane, Karrati Ilham, Hanane Zahir, Yahyaoui Hicham, Ait Ameur Mustapha, et al. (2019). Myelodysplastic Syndromes Experience of the Laboratory of the Military Hospital Avicenna Marrakech. American Journal of Laboratory Medicine, 4(6), 115-118. https://doi.org/10.11648/j.ajlm.20190406.16
ACS Style
Mouhib Hanane; Karrati Ilham; Hanane Zahir; Yahyaoui Hicham; Ait Ameur Mustapha, et al. Myelodysplastic Syndromes Experience of the Laboratory of the Military Hospital Avicenna Marrakech. Am. J. Lab. Med. 2019, 4(6), 115-118. doi: 10.11648/j.ajlm.20190406.16
AMA Style
Mouhib Hanane, Karrati Ilham, Hanane Zahir, Yahyaoui Hicham, Ait Ameur Mustapha, et al. Myelodysplastic Syndromes Experience of the Laboratory of the Military Hospital Avicenna Marrakech. Am J Lab Med. 2019;4(6):115-118. doi: 10.11648/j.ajlm.20190406.16
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Download@article{10.11648/j.ajlm.20190406.16,
author = {Mouhib Hanane and Karrati Ilham and Hanane Zahir and Yahyaoui Hicham and Ait Ameur Mustapha and Chakour Mohammed},
title = {Myelodysplastic Syndromes Experience of the Laboratory of the Military Hospital Avicenna Marrakech},
journal = {American Journal of Laboratory Medicine},
volume = {4},
number = {6},
pages = {115-118},
doi = {10.11648/j.ajlm.20190406.16},
url = {https://doi.org/10.11648/j.ajlm.20190406.16},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20190406.16},
abstract = {MDS are clonal disorders of multipotent or myeloid stem cells. The disease is characterized by inefficient hematopoiesis responsible for peripheral cytopenias and contrasting with a rich marrow. The natural course of this disease is acute myeloid leukemia (AML). This is a retrospective study on the files of patients who had a haematological assessment at the laboratory of the military hospital Avicenna Marrakech between July 2014 and July 2018 for a duration of 4 years. Included in our study were all patients with documented myelodysplasia. The average age of patients is 63.63 years with extremes of 19 years and 89 years; the sex ratio was 1.3 (17 men and 13 women). NFS was abnormal in all patients, 96.66% of whom had anemia. The myelogram was performed in all patients and allowed the diagnosis of MDS in 90% of cases. Our study shows that management needs to be further improved by selecting high-risk MDS patients, potentially candidates for allogeneic hematopoietic stem cell transplantation.},
year = {2019}
}
TY - JOUR T1 - Myelodysplastic Syndromes Experience of the Laboratory of the Military Hospital Avicenna Marrakech AU - Mouhib Hanane AU - Karrati Ilham AU - Hanane Zahir AU - Yahyaoui Hicham AU - Ait Ameur Mustapha AU - Chakour Mohammed Y1 - 2019/12/13 PY - 2019 N1 - https://doi.org/10.11648/j.ajlm.20190406.16 DO - 10.11648/j.ajlm.20190406.16 T2 - American Journal of Laboratory Medicine JF - American Journal of Laboratory Medicine JO - American Journal of Laboratory Medicine SP - 115 EP - 118 PB - Science Publishing Group SN - 2575-386X UR - https://doi.org/10.11648/j.ajlm.20190406.16 AB - MDS are clonal disorders of multipotent or myeloid stem cells. The disease is characterized by inefficient hematopoiesis responsible for peripheral cytopenias and contrasting with a rich marrow. The natural course of this disease is acute myeloid leukemia (AML). This is a retrospective study on the files of patients who had a haematological assessment at the laboratory of the military hospital Avicenna Marrakech between July 2014 and July 2018 for a duration of 4 years. Included in our study were all patients with documented myelodysplasia. The average age of patients is 63.63 years with extremes of 19 years and 89 years; the sex ratio was 1.3 (17 men and 13 women). NFS was abnormal in all patients, 96.66% of whom had anemia. The myelogram was performed in all patients and allowed the diagnosis of MDS in 90% of cases. Our study shows that management needs to be further improved by selecting high-risk MDS patients, potentially candidates for allogeneic hematopoietic stem cell transplantation. VL - 4 IS - 6 ER -
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