Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches

Bobai Mathew; Ugboko Harriet; Kadiri Olobo Sunday

doi:doi:10.11648/j.ajlm.20170204.12

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Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches

Bobai Mathew, Ugboko Harriet, Kadiri Olobo Sunday

Published in American Journal of Laboratory Medicine (Volume 2, Issue 4)

Received: 19 August 2017 Accepted: 7 September 2017 Published: 17 October 2017

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Abstract

In developing countries, the frequent failure of the available phenotypic approaches for laboratory diagnosis of urinary tract infections in providing results at the point where medical care is mostly required, becomes a major barrier to efficient antibiotic treatment and management of urinary tract infections in the public health sector. This review therefore focuses on molecular and imaging diagnostic techniques for urinary tract infection as rapid and effective modern approaches requires in health care delivery. Currently, available laboratory diagnoses of urinary tract infection in developing countries are mostly phenotypic approaches, and takes not less than two-four days before completion and result made available for appropriate treatment. From literature, it is apparent that these old-century approaches produce portion of patients’ result that does not fit the true picture; and the techniques had been found with more disadvantages than advantages. Molecular approaches are now emerging as modern laboratory test techniques which enable rapid and effective diagnosis of urinary tract infection with Biosensor, Microfluidics, Polymerase Chain Reaction (PCR) and other integrated platforms technologies. These emerging technologies could improve urinary tract infection diagnosis via direct pathogen detection from urine samples, rapid antimicrobial susceptibility testing, high precision and point of care testing in public health sector. Imaging techniques have also been so useful in identifying risk factors and abnormalities that can be modified; to decrease likelihood of recurrent (upper) UTI; and to reduce risk of renal scarring. These approaches however, had proved so successful that seems they will replace old-century testing methods, and hence, provides efficient antibiotic treatment and management; therefore, saving health care costs and valuable diagnosis time.

Published in	American Journal of Laboratory Medicine (Volume 2, Issue 4)
DOI	10.11648/j.ajlm.20170204.12
Page(s)	45-51
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

UTI, Molecular, Imaging, Laboratory, Diagnostic Techniques, Point of Care

References

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APA Style

Bobai Mathew, Ugboko Harriet, Kadiri Olobo Sunday. (2017). Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches. American Journal of Laboratory Medicine, 2(4), 45-51. https://doi.org/10.11648/j.ajlm.20170204.12

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ACS Style

Bobai Mathew; Ugboko Harriet; Kadiri Olobo Sunday. Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches. Am. J. Lab. Med. 2017, 2(4), 45-51. doi: 10.11648/j.ajlm.20170204.12

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AMA Style

Bobai Mathew, Ugboko Harriet, Kadiri Olobo Sunday. Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches. Am J Lab Med. 2017;2(4):45-51. doi: 10.11648/j.ajlm.20170204.12

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@article{10.11648/j.ajlm.20170204.12,
  author = {Bobai Mathew and Ugboko Harriet and Kadiri Olobo Sunday},
  title = {Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches},
  journal = {American Journal of Laboratory Medicine},
  volume = {2},
  number = {4},
  pages = {45-51},
  doi = {10.11648/j.ajlm.20170204.12},
  url = {https://doi.org/10.11648/j.ajlm.20170204.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20170204.12},
  abstract = {In developing countries, the frequent failure of the available phenotypic approaches for laboratory diagnosis of urinary tract infections in providing results at the point where medical care is mostly required, becomes a major barrier to efficient antibiotic treatment and management of urinary tract infections in the public health sector. This review therefore focuses on molecular and imaging diagnostic techniques for urinary tract infection as rapid and effective modern approaches requires in health care delivery. Currently, available laboratory diagnoses of urinary tract infection in developing countries are mostly phenotypic approaches, and takes not less than two-four days before completion and result made available for appropriate treatment. From literature, it is apparent that these old-century approaches produce portion of patients’ result that does not fit the true picture; and the techniques had been found with more disadvantages than advantages. Molecular approaches are now emerging as modern laboratory test techniques which enable rapid and effective diagnosis of urinary tract infection with Biosensor, Microfluidics, Polymerase Chain Reaction (PCR) and other integrated platforms technologies. These emerging technologies could improve urinary tract infection diagnosis via direct pathogen detection from urine samples, rapid antimicrobial susceptibility testing, high precision and point of care testing in public health sector. Imaging techniques have also been so useful in identifying risk factors and abnormalities that can be modified; to decrease likelihood of recurrent (upper) UTI; and to reduce risk of renal scarring. These approaches however, had proved so successful that seems they will replace old-century testing methods, and hence, provides efficient antibiotic treatment and management; therefore, saving health care costs and valuable diagnosis time.},
 year = {2017}
}

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TY  - JOUR
T1  - Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches
AU  - Bobai Mathew
AU  - Ugboko Harriet
AU  - Kadiri Olobo Sunday
Y1  - 2017/10/17
PY  - 2017
N1  - https://doi.org/10.11648/j.ajlm.20170204.12
DO  - 10.11648/j.ajlm.20170204.12
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 45
EP  - 51
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20170204.12
AB  - In developing countries, the frequent failure of the available phenotypic approaches for laboratory diagnosis of urinary tract infections in providing results at the point where medical care is mostly required, becomes a major barrier to efficient antibiotic treatment and management of urinary tract infections in the public health sector. This review therefore focuses on molecular and imaging diagnostic techniques for urinary tract infection as rapid and effective modern approaches requires in health care delivery. Currently, available laboratory diagnoses of urinary tract infection in developing countries are mostly phenotypic approaches, and takes not less than two-four days before completion and result made available for appropriate treatment. From literature, it is apparent that these old-century approaches produce portion of patients’ result that does not fit the true picture; and the techniques had been found with more disadvantages than advantages. Molecular approaches are now emerging as modern laboratory test techniques which enable rapid and effective diagnosis of urinary tract infection with Biosensor, Microfluidics, Polymerase Chain Reaction (PCR) and other integrated platforms technologies. These emerging technologies could improve urinary tract infection diagnosis via direct pathogen detection from urine samples, rapid antimicrobial susceptibility testing, high precision and point of care testing in public health sector. Imaging techniques have also been so useful in identifying risk factors and abnormalities that can be modified; to decrease likelihood of recurrent (upper) UTI; and to reduce risk of renal scarring. These approaches however, had proved so successful that seems they will replace old-century testing methods, and hence, provides efficient antibiotic treatment and management; therefore, saving health care costs and valuable diagnosis time.
VL  - 2
IS  - 4
ER  -

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Author Information

Bobai Mathew

Department of Microbiology, Faculty of Science, Kaduna State University, Kaduna, Nigeria
Ugboko Harriet

Department of Biological Sciences, Faculty of Science, Covenant University, Canaanland, Ota, Nigeria
Kadiri Olobo Sunday

Department of Microbiology and Biotechnology, Faculty of Science, Federal University Dutse, Dutse, Nigeria

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APA Style

Bobai Mathew, Ugboko Harriet, Kadiri Olobo Sunday. (2017). Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches. American Journal of Laboratory Medicine, 2(4), 45-51. https://doi.org/10.11648/j.ajlm.20170204.12

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ACS Style

Bobai Mathew; Ugboko Harriet; Kadiri Olobo Sunday. Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches. Am. J. Lab. Med. 2017, 2(4), 45-51. doi: 10.11648/j.ajlm.20170204.12

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AMA Style

Bobai Mathew, Ugboko Harriet, Kadiri Olobo Sunday. Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches. Am J Lab Med. 2017;2(4):45-51. doi: 10.11648/j.ajlm.20170204.12

Copy | Download

@article{10.11648/j.ajlm.20170204.12,
  author = {Bobai Mathew and Ugboko Harriet and Kadiri Olobo Sunday},
  title = {Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches},
  journal = {American Journal of Laboratory Medicine},
  volume = {2},
  number = {4},
  pages = {45-51},
  doi = {10.11648/j.ajlm.20170204.12},
  url = {https://doi.org/10.11648/j.ajlm.20170204.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20170204.12},
  abstract = {In developing countries, the frequent failure of the available phenotypic approaches for laboratory diagnosis of urinary tract infections in providing results at the point where medical care is mostly required, becomes a major barrier to efficient antibiotic treatment and management of urinary tract infections in the public health sector. This review therefore focuses on molecular and imaging diagnostic techniques for urinary tract infection as rapid and effective modern approaches requires in health care delivery. Currently, available laboratory diagnoses of urinary tract infection in developing countries are mostly phenotypic approaches, and takes not less than two-four days before completion and result made available for appropriate treatment. From literature, it is apparent that these old-century approaches produce portion of patients’ result that does not fit the true picture; and the techniques had been found with more disadvantages than advantages. Molecular approaches are now emerging as modern laboratory test techniques which enable rapid and effective diagnosis of urinary tract infection with Biosensor, Microfluidics, Polymerase Chain Reaction (PCR) and other integrated platforms technologies. These emerging technologies could improve urinary tract infection diagnosis via direct pathogen detection from urine samples, rapid antimicrobial susceptibility testing, high precision and point of care testing in public health sector. Imaging techniques have also been so useful in identifying risk factors and abnormalities that can be modified; to decrease likelihood of recurrent (upper) UTI; and to reduce risk of renal scarring. These approaches however, had proved so successful that seems they will replace old-century testing methods, and hence, provides efficient antibiotic treatment and management; therefore, saving health care costs and valuable diagnosis time.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Molecular and Imaging Diagnostic Techniques for Urinary Tract Infections: Modern Approaches
AU  - Bobai Mathew
AU  - Ugboko Harriet
AU  - Kadiri Olobo Sunday
Y1  - 2017/10/17
PY  - 2017
N1  - https://doi.org/10.11648/j.ajlm.20170204.12
DO  - 10.11648/j.ajlm.20170204.12
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 45
EP  - 51
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20170204.12
AB  - In developing countries, the frequent failure of the available phenotypic approaches for laboratory diagnosis of urinary tract infections in providing results at the point where medical care is mostly required, becomes a major barrier to efficient antibiotic treatment and management of urinary tract infections in the public health sector. This review therefore focuses on molecular and imaging diagnostic techniques for urinary tract infection as rapid and effective modern approaches requires in health care delivery. Currently, available laboratory diagnoses of urinary tract infection in developing countries are mostly phenotypic approaches, and takes not less than two-four days before completion and result made available for appropriate treatment. From literature, it is apparent that these old-century approaches produce portion of patients’ result that does not fit the true picture; and the techniques had been found with more disadvantages than advantages. Molecular approaches are now emerging as modern laboratory test techniques which enable rapid and effective diagnosis of urinary tract infection with Biosensor, Microfluidics, Polymerase Chain Reaction (PCR) and other integrated platforms technologies. These emerging technologies could improve urinary tract infection diagnosis via direct pathogen detection from urine samples, rapid antimicrobial susceptibility testing, high precision and point of care testing in public health sector. Imaging techniques have also been so useful in identifying risk factors and abnormalities that can be modified; to decrease likelihood of recurrent (upper) UTI; and to reduce risk of renal scarring. These approaches however, had proved so successful that seems they will replace old-century testing methods, and hence, provides efficient antibiotic treatment and management; therefore, saving health care costs and valuable diagnosis time.
VL  - 2
IS  - 4
ER  -

Copy | Download