Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia

Endrias Markos Woldesemayat

doi:doi:10.11648/j.ajcem.20210902.11

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Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia

Endrias Markos Woldesemayat

Published in American Journal of Clinical and Experimental Medicine (Volume 9, Issue 2)

Received: 28 January 2021 Accepted: 26 February 2021 Published: 1 April 2021

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Abstract

Background: Estimating TB incidence rate using follow-up study has not been done in southern Ethiopia. Objective: The aim of this study was to estimate incidence rate of smear-positive TB in Dale district, Sidama Region, South Ethiopia. Methods: In a cohort study conducted among 36,575 people in six rural communities: 14,801 children, 92 cases with history of TB treatment and 15 smear-positive TB cases were excluded from the cohort. For 648 smear-negative patients with symptoms of TB and 1443 neighbourhood controls, we did a 3 – 4 monthly follow-up surveys and detected TB cases. For the rest of population, at the end of the follow-up, identification of TB cases from the district TB register was done. Results: In this study, 21,667 adult people were followed for 18,031 person-years and detected 49 new TB cases. Incidence rate of smear-positive TB was (273; 95% CI: 206 – 361)/100,000 person-years. The risk of smear-positive TB was higher among illiterate people (Adjusted incidence rate ratio 2.4; 95% CI 1.2 – 5.0). Conclusion: TB continued to be a major public health problem in rural communities of South Ethiopia. A high incidence rate of smear-positive TB was observed in the study settings. To improve specificity of the diagnosis, future studies should consider using sputum culture or GeneXpert in screening and diagnosis of TB.

Published in	American Journal of Clinical and Experimental Medicine (Volume 9, Issue 2)
DOI	10.11648/j.ajcem.20210902.11
Page(s)	22-27
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Follow-up, Incidence Rate, Ethiopia, TB

References

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APA Style

Endrias Markos Woldesemayat. (2021). Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia. American Journal of Clinical and Experimental Medicine, 9(2), 22-27. https://doi.org/10.11648/j.ajcem.20210902.11

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Endrias Markos Woldesemayat. Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia. Am. J. Clin. Exp. Med. 2021, 9(2), 22-27. doi: 10.11648/j.ajcem.20210902.11

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AMA Style

Endrias Markos Woldesemayat. Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia. Am J Clin Exp Med. 2021;9(2):22-27. doi: 10.11648/j.ajcem.20210902.11

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@article{10.11648/j.ajcem.20210902.11,
  author = {Endrias Markos Woldesemayat},
  title = {Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {9},
  number = {2},
  pages = {22-27},
  doi = {10.11648/j.ajcem.20210902.11},
  url = {https://doi.org/10.11648/j.ajcem.20210902.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20210902.11},
  abstract = {Background: Estimating TB incidence rate using follow-up study has not been done in southern Ethiopia. Objective: The aim of this study was to estimate incidence rate of smear-positive TB in Dale district, Sidama Region, South Ethiopia. Methods: In a cohort study conducted among 36,575 people in six rural communities: 14,801 children, 92 cases with history of TB treatment and 15 smear-positive TB cases were excluded from the cohort. For 648 smear-negative patients with symptoms of TB and 1443 neighbourhood controls, we did a 3 – 4 monthly follow-up surveys and detected TB cases. For the rest of population, at the end of the follow-up, identification of TB cases from the district TB register was done. Results: In this study, 21,667 adult people were followed for 18,031 person-years and detected 49 new TB cases. Incidence rate of smear-positive TB was (273; 95% CI: 206 – 361)/100,000 person-years. The risk of smear-positive TB was higher among illiterate people (Adjusted incidence rate ratio 2.4; 95% CI 1.2 – 5.0). Conclusion: TB continued to be a major public health problem in rural communities of South Ethiopia. A high incidence rate of smear-positive TB was observed in the study settings. To improve specificity of the diagnosis, future studies should consider using sputum culture or GeneXpert in screening and diagnosis of TB.},
 year = {2021}
}

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TY  - JOUR
T1  - Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia
AU  - Endrias Markos Woldesemayat
Y1  - 2021/04/01
PY  - 2021
N1  - https://doi.org/10.11648/j.ajcem.20210902.11
DO  - 10.11648/j.ajcem.20210902.11
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 22
EP  - 27
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20210902.11
AB  - Background: Estimating TB incidence rate using follow-up study has not been done in southern Ethiopia. Objective: The aim of this study was to estimate incidence rate of smear-positive TB in Dale district, Sidama Region, South Ethiopia. Methods: In a cohort study conducted among 36,575 people in six rural communities: 14,801 children, 92 cases with history of TB treatment and 15 smear-positive TB cases were excluded from the cohort. For 648 smear-negative patients with symptoms of TB and 1443 neighbourhood controls, we did a 3 – 4 monthly follow-up surveys and detected TB cases. For the rest of population, at the end of the follow-up, identification of TB cases from the district TB register was done. Results: In this study, 21,667 adult people were followed for 18,031 person-years and detected 49 new TB cases. Incidence rate of smear-positive TB was (273; 95% CI: 206 – 361)/100,000 person-years. The risk of smear-positive TB was higher among illiterate people (Adjusted incidence rate ratio 2.4; 95% CI 1.2 – 5.0). Conclusion: TB continued to be a major public health problem in rural communities of South Ethiopia. A high incidence rate of smear-positive TB was observed in the study settings. To improve specificity of the diagnosis, future studies should consider using sputum culture or GeneXpert in screening and diagnosis of TB.
VL  - 9
IS  - 2
ER  -

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Author Information

Endrias Markos Woldesemayat

School of Public Health, Hawassa University, Hawassa, Ethiopia

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Plain Text BibTeX RIS

APA Style

Endrias Markos Woldesemayat. (2021). Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia. American Journal of Clinical and Experimental Medicine, 9(2), 22-27. https://doi.org/10.11648/j.ajcem.20210902.11

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ACS Style

Endrias Markos Woldesemayat. Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia. Am. J. Clin. Exp. Med. 2021, 9(2), 22-27. doi: 10.11648/j.ajcem.20210902.11

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AMA Style

Endrias Markos Woldesemayat. Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia. Am J Clin Exp Med. 2021;9(2):22-27. doi: 10.11648/j.ajcem.20210902.11

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@article{10.11648/j.ajcem.20210902.11,
  author = {Endrias Markos Woldesemayat},
  title = {Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {9},
  number = {2},
  pages = {22-27},
  doi = {10.11648/j.ajcem.20210902.11},
  url = {https://doi.org/10.11648/j.ajcem.20210902.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20210902.11},
  abstract = {Background: Estimating TB incidence rate using follow-up study has not been done in southern Ethiopia. Objective: The aim of this study was to estimate incidence rate of smear-positive TB in Dale district, Sidama Region, South Ethiopia. Methods: In a cohort study conducted among 36,575 people in six rural communities: 14,801 children, 92 cases with history of TB treatment and 15 smear-positive TB cases were excluded from the cohort. For 648 smear-negative patients with symptoms of TB and 1443 neighbourhood controls, we did a 3 – 4 monthly follow-up surveys and detected TB cases. For the rest of population, at the end of the follow-up, identification of TB cases from the district TB register was done. Results: In this study, 21,667 adult people were followed for 18,031 person-years and detected 49 new TB cases. Incidence rate of smear-positive TB was (273; 95% CI: 206 – 361)/100,000 person-years. The risk of smear-positive TB was higher among illiterate people (Adjusted incidence rate ratio 2.4; 95% CI 1.2 – 5.0). Conclusion: TB continued to be a major public health problem in rural communities of South Ethiopia. A high incidence rate of smear-positive TB was observed in the study settings. To improve specificity of the diagnosis, future studies should consider using sputum culture or GeneXpert in screening and diagnosis of TB.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Incidence of Smear-positive Tuberculosis in Dale District, Sidama, South Ethiopia
AU  - Endrias Markos Woldesemayat
Y1  - 2021/04/01
PY  - 2021
N1  - https://doi.org/10.11648/j.ajcem.20210902.11
DO  - 10.11648/j.ajcem.20210902.11
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 22
EP  - 27
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20210902.11
AB  - Background: Estimating TB incidence rate using follow-up study has not been done in southern Ethiopia. Objective: The aim of this study was to estimate incidence rate of smear-positive TB in Dale district, Sidama Region, South Ethiopia. Methods: In a cohort study conducted among 36,575 people in six rural communities: 14,801 children, 92 cases with history of TB treatment and 15 smear-positive TB cases were excluded from the cohort. For 648 smear-negative patients with symptoms of TB and 1443 neighbourhood controls, we did a 3 – 4 monthly follow-up surveys and detected TB cases. For the rest of population, at the end of the follow-up, identification of TB cases from the district TB register was done. Results: In this study, 21,667 adult people were followed for 18,031 person-years and detected 49 new TB cases. Incidence rate of smear-positive TB was (273; 95% CI: 206 – 361)/100,000 person-years. The risk of smear-positive TB was higher among illiterate people (Adjusted incidence rate ratio 2.4; 95% CI 1.2 – 5.0). Conclusion: TB continued to be a major public health problem in rural communities of South Ethiopia. A high incidence rate of smear-positive TB was observed in the study settings. To improve specificity of the diagnosis, future studies should consider using sputum culture or GeneXpert in screening and diagnosis of TB.
VL  - 9
IS  - 2
ER  -

Copy | Download