The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain

Zhenhua Huang; Qianlin Gu; Hong Zhan; Zhen Yang; Yuee Chen

doi:doi:10.11648/j.ajcem.20200801.11

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The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain

Zhenhua Huang, Qianlin Gu, Hong Zhan, Zhen Yang, Yuee Chen

Published in American Journal of Clinical and Experimental Medicine (Volume 8, Issue 1)

Received: 31 January 2020 Accepted: 18 February 2020 Published: 26 February 2020

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Abstract

To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (P<0.05). The predictive ROC curve area of GRACE scores in 30-day MACE was 0.739 (0.687 to 0.791). The probability of 30-day cardiovascular adverse events in various GRACE score risk stratification was 2.0% (low-risk), 5.33% (medium-risk), and 9.67% (high-risk), respectively. The GRACE score was a useful predictor to the occurrence of 30-day cardiovascular adverse events in acute chest pain patients. Patients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.

Published in	American Journal of Clinical and Experimental Medicine (Volume 8, Issue 1)
DOI	10.11648/j.ajcem.20200801.11
Page(s)	1-5
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

GRACE Scores, Acute Chest Pain, Risk Stratification, Cardiovascular Adverse Events

References

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APA Style

Zhenhua Huang, Qianlin Gu, Hong Zhan, Zhen Yang, Yuee Chen. (2020). The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. American Journal of Clinical and Experimental Medicine, 8(1), 1-5. https://doi.org/10.11648/j.ajcem.20200801.11

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ACS Style

Zhenhua Huang; Qianlin Gu; Hong Zhan; Zhen Yang; Yuee Chen. The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. Am. J. Clin. Exp. Med. 2020, 8(1), 1-5. doi: 10.11648/j.ajcem.20200801.11

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AMA Style

Zhenhua Huang, Qianlin Gu, Hong Zhan, Zhen Yang, Yuee Chen. The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. Am J Clin Exp Med. 2020;8(1):1-5. doi: 10.11648/j.ajcem.20200801.11

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@article{10.11648/j.ajcem.20200801.11,
  author = {Zhenhua Huang and Qianlin Gu and Hong Zhan and Zhen Yang and Yuee Chen},
  title = {The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {8},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.ajcem.20200801.11},
  url = {https://doi.org/10.11648/j.ajcem.20200801.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20200801.11},
  abstract = {To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (PPatients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.},
 year = {2020}
}

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TY  - JOUR
T1  - The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain
AU  - Zhenhua Huang
AU  - Qianlin Gu
AU  - Hong Zhan
AU  - Zhen Yang
AU  - Yuee Chen
Y1  - 2020/02/26
PY  - 2020
N1  - https://doi.org/10.11648/j.ajcem.20200801.11
DO  - 10.11648/j.ajcem.20200801.11
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20200801.11
AB  - To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (PPatients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.
VL  - 8
IS  - 1
ER  -

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Author Information

Zhenhua Huang

Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
Qianlin Gu

Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
Hong Zhan

Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
Zhen Yang

Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China
Yuee Chen

Emergency Department, The First Affiliated Hospital of Sun Sat-sen University, Guangzhou, China

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APA Style

Zhenhua Huang, Qianlin Gu, Hong Zhan, Zhen Yang, Yuee Chen. (2020). The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. American Journal of Clinical and Experimental Medicine, 8(1), 1-5. https://doi.org/10.11648/j.ajcem.20200801.11

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ACS Style

Zhenhua Huang; Qianlin Gu; Hong Zhan; Zhen Yang; Yuee Chen. The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. Am. J. Clin. Exp. Med. 2020, 8(1), 1-5. doi: 10.11648/j.ajcem.20200801.11

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AMA Style

Zhenhua Huang, Qianlin Gu, Hong Zhan, Zhen Yang, Yuee Chen. The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain. Am J Clin Exp Med. 2020;8(1):1-5. doi: 10.11648/j.ajcem.20200801.11

Copy | Download

@article{10.11648/j.ajcem.20200801.11,
  author = {Zhenhua Huang and Qianlin Gu and Hong Zhan and Zhen Yang and Yuee Chen},
  title = {The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {8},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.ajcem.20200801.11},
  url = {https://doi.org/10.11648/j.ajcem.20200801.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20200801.11},
  abstract = {To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (PPatients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - The Effect of GRACE Scores on Prediction of 30-day Cardiovascular Adverse Events in Patients with Acute Chest Pain
AU  - Zhenhua Huang
AU  - Qianlin Gu
AU  - Hong Zhan
AU  - Zhen Yang
AU  - Yuee Chen
Y1  - 2020/02/26
PY  - 2020
N1  - https://doi.org/10.11648/j.ajcem.20200801.11
DO  - 10.11648/j.ajcem.20200801.11
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20200801.11
AB  - To investigate the effect of GRACE scores on prediction of 30-day cardiovascular adverse events in acute chest pain patients. A prospective, observational analysis was conducted in the patients with acute chest pain in Emergency Department (ED) from January 1, 2016 through January 1, 2017. Data including characteristics and GRACE scores were collected. All causes leading to MACE were followed up at 30th day after the onset of acute chest pain. Among a total of 600 patients presenting with acute chest pain enrolled in this study, 302 were male (50.3%) and 298 were female (49.7%). The range of age was 20-80 years old. During follow-up period, 102 patients had MACE, 498 patients had no MACE. When compared with non-MACE group, factors including number of Smoker, Hypercholesterolemia, Diabetes, Hypercholesterolemia and patients admitted in CCU as well as GRACE scores, were significantly higher in MACE group (PPatients with low GRACE score risk stratification have a low risk of 30-day MACE, which may be able to convey risk quickly and efficiently.
VL  - 8
IS  - 1
ER  -

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