| Peer-Reviewed

Relationship Between No/Slow Reflow Phenomenon in Acute Myocardial Infarction Patients After Percutaneous Coronary Intervention and Inflammatory Response

Received: 26 August 2019     Published: 27 September 2019
Views:       Downloads:
Abstract

Background: To explore the relationship between the occurrence of no/slow reflow phenomenon in acute myocardial infarction patients after undergoing percutaneous coronary intervention (PCI) and inflammatory response. Objective: Prospective study was conducted on 519 acute myocardial infarction patients undergoing PCI, in which 509 patients were followed up for one year. Method: The 76 cases with no/slow reflow phenomenon after PCI was the adverse reflow group. One hundred patients were randomly selected from the remaining 443 patients with the Excel random function table as the control group to avoid statistical deviation. Result: The inflammatory indicators, such as the total numbers of white blood cells and neutrophils, high-sensitivity C-reactive protein, mortality, adverse cardiac event. Conclusion: Inflammatory response is related to the occurrence of no/slow reflow phenomenon in acute myocardial infarction patients after PCI, and seriously affects their prognosis.

Published in American Journal of Clinical and Experimental Medicine (Volume 7, Issue 4)
DOI 10.11648/j.ajcem.20190704.13
Page(s) 93-96
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Acute Myocardial Infarction, No/Slow Reflow, Direct PCI, Inflammatory Response

References
[1] Ambrose JA. Editorial: Managing Coronary Thrombus in the Cath Lab During PCI. Curr Cardiol Rev, 2018, 8: 200-1.
[2] Lazzeri C, Valente S, Chiostri M, Attanà P, Mattesini A, Dini CS, Gensini GF. Comorbidities in stemi patients submitted to primary PCI: Temporal trends and impact on mortality: A 6-year single center experience. Int J Cardiol, 2019, 11 (8): 256-31.
[3] Balghith MA. High Bolus Tirofiban vs Abciximab in Acute STEMI Patients Undergoing Primary PCI - The Tamip Study. Heart Views, 2018, 13 (3): 85-90.
[4] Palmerini T, Genereux P, Caixeta A, Cristea E, Lansky A, Mehran R, Della Riva D, Fahy M, Xu K, Stone GW. A New Score for Risk Stratification of Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention: The ACUITY-PCI (Acute Catheterization and Urgent Intervention Triage Strategy-Percutaneous Coronary Intervention) Risk Score. JACC Cardiovasc Interv, 2019, 5 (11): 1108-16.
[5] Cohn JN. Fractional flow reserve-guided PCI reduced urgent revascularization at 7 months in coronary artery disease. Ann Intern Med, 157 (10): 5-9.
[6] Huang RL, Thomassee EJ, Park JY, Scott C, Maron DJ, Fredi JL. Clinical Pathway: Helicopter Scene STEMI Protocol to Facilitate Long-Distance Transfer for Primary PCI. Crit Pathw Cardiol, 2019, 11 (4): 193-8.
[7] Jhaveri RR, Reynolds HR, Katz SD, Jeger R, Zinka E, Forman SA, Lamas GA, Hochman JS. Heart Failure in Post-MI Patients With Persistent IRA Occlusion: Prevalence, Risk Factors, and the Long-Term Effect of PCI in the Occluded Artery Trial (OAT). J Card Fail, 2018, 18 (11): 813-21.
[8] Giordano V, Grandjean JG. There is always hope after PCI and stenting. J Cardiovasc Med (Hagerstown), 2019, 13 (11): 766-8.
[9] Knot J, Kala P, Rokyta R, Stasek J, Kuzmanov B, Hlinomaz O, Bĕlohlavek J, Rohac FP, Petr R, Bilkova D, Djambazov S, Grigorov M, Widimsky P. Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: data from a multicentre registry. Cardiovasc J Afr, 2018, 23 (9): 495-500.
[10] Kherada N, Mehran R. Impending savior: Impella 2.5 circulatory support system in high-risk PCI. Catheter Cardiovasc Interv, 2017, 80 (5): 726-7.
[11] Healey JS. Trifecta or Triple Threat? The Challenge of Post-PCI Management in Patients Receiving Chronic Oral Anticoagulant Therapy. Can J Cardiol, 2019, 11 (2): 641-5.
[12] Moscucci M. Public reporting of PCI outcomes and quality of care: one step forward and new questions raised. JAMA, 2018, 308 (14): 1478-9.
[13] Chakrabarti AK, Gibson CM. Optimal selection of STEMI treatment strategies in the current era: benefit of transferring STEMI patients for PCI compared with administration of onsite fibrinolytic therapy. Curr Opin Cardiol, 2019, 27 (6): 651-4.
[14] Berstad MB, Weyergang A, Berg K. Photochemical internalization (PCI) of HER2-targeted toxins: Synergy is dependent on the treatment sequence. Biochim Biophys Acta, 2017, 1820 (12): 1849-58.
[15] Jerónimo Sousa P, Campante Teles R, Brito J, Abecasis J, de Araújo Gonçalves P, Calé R, Leal S, Dourado R, Raposo L, Silva A, Almeida M, Mendes M. Primary PCI in ST-elevation myocardial infarction: Mode of referral and time to PCI. Rev Port Cardiol, 2017, 31 (10): 641-646.
[16] Meier P, Froehlich GM, Yellon DM, Hausenloy DJ. Predicting peri-procedural myocardial infarction during PCI. Heart, 2018, 98 (20): 1471-2.
[17] Srikanth S, Ambrose JA. Pathophysiology of Coronary Thrombus Formation and Adverse Consequences of Thrombus During PCI. Curr Cardiol Rev, 2018, 8 (3): 168-76.
Cite This Article
  • APA Style

    Binbin Wang, Zhi Xiao, Nana Peng. (2019). Relationship Between No/Slow Reflow Phenomenon in Acute Myocardial Infarction Patients After Percutaneous Coronary Intervention and Inflammatory Response. American Journal of Clinical and Experimental Medicine, 7(4), 93-96. https://doi.org/10.11648/j.ajcem.20190704.13

    Copy | Download

    ACS Style

    Binbin Wang; Zhi Xiao; Nana Peng. Relationship Between No/Slow Reflow Phenomenon in Acute Myocardial Infarction Patients After Percutaneous Coronary Intervention and Inflammatory Response. Am. J. Clin. Exp. Med. 2019, 7(4), 93-96. doi: 10.11648/j.ajcem.20190704.13

    Copy | Download

    AMA Style

    Binbin Wang, Zhi Xiao, Nana Peng. Relationship Between No/Slow Reflow Phenomenon in Acute Myocardial Infarction Patients After Percutaneous Coronary Intervention and Inflammatory Response. Am J Clin Exp Med. 2019;7(4):93-96. doi: 10.11648/j.ajcem.20190704.13

    Copy | Download

  • @article{10.11648/j.ajcem.20190704.13,
      author = {Binbin Wang and Zhi Xiao and Nana Peng},
      title = {Relationship Between No/Slow Reflow Phenomenon in Acute Myocardial Infarction Patients After Percutaneous Coronary Intervention and Inflammatory Response},
      journal = {American Journal of Clinical and Experimental Medicine},
      volume = {7},
      number = {4},
      pages = {93-96},
      doi = {10.11648/j.ajcem.20190704.13},
      url = {https://doi.org/10.11648/j.ajcem.20190704.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20190704.13},
      abstract = {Background: To explore the relationship between the occurrence of no/slow reflow phenomenon in acute myocardial infarction patients after undergoing percutaneous coronary intervention (PCI) and inflammatory response. Objective: Prospective study was conducted on 519 acute myocardial infarction patients undergoing PCI, in which 509 patients were followed up for one year. Method: The 76 cases with no/slow reflow phenomenon after PCI was the adverse reflow group. One hundred patients were randomly selected from the remaining 443 patients with the Excel random function table as the control group to avoid statistical deviation. Result: The inflammatory indicators, such as the total numbers of white blood cells and neutrophils, high-sensitivity C-reactive protein, mortality, adverse cardiac event. Conclusion: Inflammatory response is related to the occurrence of no/slow reflow phenomenon in acute myocardial infarction patients after PCI, and seriously affects their prognosis.},
     year = {2019}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Relationship Between No/Slow Reflow Phenomenon in Acute Myocardial Infarction Patients After Percutaneous Coronary Intervention and Inflammatory Response
    AU  - Binbin Wang
    AU  - Zhi Xiao
    AU  - Nana Peng
    Y1  - 2019/09/27
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ajcem.20190704.13
    DO  - 10.11648/j.ajcem.20190704.13
    T2  - American Journal of Clinical and Experimental Medicine
    JF  - American Journal of Clinical and Experimental Medicine
    JO  - American Journal of Clinical and Experimental Medicine
    SP  - 93
    EP  - 96
    PB  - Science Publishing Group
    SN  - 2330-8133
    UR  - https://doi.org/10.11648/j.ajcem.20190704.13
    AB  - Background: To explore the relationship between the occurrence of no/slow reflow phenomenon in acute myocardial infarction patients after undergoing percutaneous coronary intervention (PCI) and inflammatory response. Objective: Prospective study was conducted on 519 acute myocardial infarction patients undergoing PCI, in which 509 patients were followed up for one year. Method: The 76 cases with no/slow reflow phenomenon after PCI was the adverse reflow group. One hundred patients were randomly selected from the remaining 443 patients with the Excel random function table as the control group to avoid statistical deviation. Result: The inflammatory indicators, such as the total numbers of white blood cells and neutrophils, high-sensitivity C-reactive protein, mortality, adverse cardiac event. Conclusion: Inflammatory response is related to the occurrence of no/slow reflow phenomenon in acute myocardial infarction patients after PCI, and seriously affects their prognosis.
    VL  - 7
    IS  - 4
    ER  - 

    Copy | Download

Author Information
  • Emergency Department, Binzhou People's Hospital, Binzhou City, P. R. China

  • Department of Nephrology, Binzhou People's Hospital, Binzhou City, P. R. China

  • Emergency Department, Binzhou People's Hospital, Binzhou City, P. R. China

  • Sections