Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children

Esam-eddin Bakhei Mohamed Ahmed; Nagah Abd Elwehab Ahmed Mohamed; Faroug Bakheit Mohamed Ahmed; Mashair Abdelgadir; Safa Ahmed Ali

doi:doi:10.11648/j.ajcem.20150306.12

Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children

Esam-eddin Bakhei Mohamed Ahmed, Nagah Abd Elwehab Ahmed Mohamed, Faroug Bakheit Mohamed Ahmed, Mashair Abdelgadir, Safa Ahmed Ali

Published in American Journal of Clinical and Experimental Medicine (Volume 3, Issue 6)

Received: 10 October 2015 Accepted: 26 October 2015 Published: 7 December 2015

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Abstract

Current study aims to compare hematological parameters between children with febrile seizures and to find their common etiology among Sudanese children. In a case control study 150 children who were admitted to Gafar Ibn-Ouf pediatrics specialized hospital and Omdurman emergency pediatrics hospital during the period from Jun- Aug 2015 were studied. This study showed low levels of all hematological parameters in febrile seizures patients with exception of red distribution width (RDW), platelets and total iron binding capacity (TIBC) compared to their reference copartners. This evidence can be regarded as a risk factor for seizures in febrile children. The study also detected that children with low hematological levels of these parameters had a family history of febrile seizures and the consanguinity was associated with higher peak body temperature.

Published in	American Journal of Clinical and Experimental Medicine (Volume 3, Issue 6)
DOI	10.11648/j.ajcem.20150306.12
Page(s)	332-334
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Febrile Seizures, Children, Risk Factors and Iron Status

References

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[2]	Azhar S. Daoud, Anwar Batieha, Faisel Abu-Ekteish, Nayef Gharaibeh, Saleh Ajlouni, and Saad Hijazi (2002). Iron Status: A Possible Risk Factor for the First Febrile Seizure. Epilepsia, 43(7):740–743.
[3]	Kira R, Ishizaki Y, Torisu H, et al. Genetic susceptibility to febrile seizures: case-control association studies. Brain Dev 2010; 32:57.
[4]	Nakayama J. Progress in searching for the febrile seizure susceptibility genes. Brain Dev 2009; 31:359.
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[6]	Kimia AA, Capraro AJ, Hummel D, et al. Utility of lumbar puncture for first simple febrile seizure among children 6 to 18 months of age. Pediatrics 2009; 123:6.
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[8]	Thomas EA, Hawkins RJ, Richards KL, et al. Heat opens axon initial segment sodium channels: a febrile seizure mechanism? Ann Neurol 2009; 66:219.
[9]	Schuchmann S, Schmitz D, Rivera C, et al. Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. Nat Med 2006; 12:817.
[10]	Barlow WE, Davis RL, Glasser JW, et al.The risk of seizures after receipt of whole-cell pertussis or measles, mumps, and rubella vaccine. N Engl J Med 2001; 345:656.
[11]	Subcommittee on Febrile Seizures, American Academy of Pediatrics. Neurodiagnostic evaluation of the child with a simple febrile seizure. Pediatrics 2011; 127:389.
[12]	Sherjil A, us Saeed Z, Shehzad S, Amjad R.(2010). Iron deficiency anaemia--a risk factor for febrile seizures in children. J Ayub Med Coll Abbottabad. 2010 Jul-Sep;22(3):71-3
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[16]	Kira R, Ishizaki Y, Torisu H, et al. Genetic susceptibility to febrile seizures: case-control association studies. Brain Dev 2010; 32:57.

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Esam-eddin Bakhei Mohamed Ahmed, Nagah Abd Elwehab Ahmed Mohamed, Faroug Bakheit Mohamed Ahmed, Mashair Abdelgadir, Safa Ahmed Ali. (2015). Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children. American Journal of Clinical and Experimental Medicine, 3(6), 332-334. https://doi.org/10.11648/j.ajcem.20150306.12

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ACS Style

Esam-eddin Bakhei Mohamed Ahmed; Nagah Abd Elwehab Ahmed Mohamed; Faroug Bakheit Mohamed Ahmed; Mashair Abdelgadir; Safa Ahmed Ali. Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children. Am. J. Clin. Exp. Med. 2015, 3(6), 332-334. doi: 10.11648/j.ajcem.20150306.12

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AMA Style

Esam-eddin Bakhei Mohamed Ahmed, Nagah Abd Elwehab Ahmed Mohamed, Faroug Bakheit Mohamed Ahmed, Mashair Abdelgadir, Safa Ahmed Ali. Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children. Am J Clin Exp Med. 2015;3(6):332-334. doi: 10.11648/j.ajcem.20150306.12

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@article{10.11648/j.ajcem.20150306.12,
  author = {Esam-eddin Bakhei Mohamed Ahmed and Nagah Abd Elwehab Ahmed Mohamed and Faroug Bakheit Mohamed Ahmed and Mashair Abdelgadir and Safa Ahmed Ali},
  title = {Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {3},
  number = {6},
  pages = {332-334},
  doi = {10.11648/j.ajcem.20150306.12},
  url = {https://doi.org/10.11648/j.ajcem.20150306.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20150306.12},
  abstract = {Current study aims to compare hematological parameters between children with febrile seizures and to find their common etiology among Sudanese children. In a case control study 150 children who were admitted to Gafar Ibn-Ouf pediatrics specialized hospital and Omdurman emergency pediatrics hospital during the period from Jun- Aug 2015 were studied. This study showed low levels of all hematological parameters in febrile seizures patients with exception of red distribution width (RDW), platelets and total iron binding capacity (TIBC) compared to their reference copartners. This evidence can be regarded as a risk factor for seizures in febrile children. The study also detected that children with low hematological levels of these parameters had a family history of febrile seizures and the consanguinity was associated with higher peak body temperature.},
 year = {2015}
}

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TY  - JOUR
T1  - Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children
AU  - Esam-eddin Bakhei Mohamed Ahmed
AU  - Nagah Abd Elwehab Ahmed Mohamed
AU  - Faroug Bakheit Mohamed Ahmed
AU  - Mashair Abdelgadir
AU  - Safa Ahmed Ali
Y1  - 2015/12/07
PY  - 2015
N1  - https://doi.org/10.11648/j.ajcem.20150306.12
DO  - 10.11648/j.ajcem.20150306.12
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 332
EP  - 334
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20150306.12
AB  - Current study aims to compare hematological parameters between children with febrile seizures and to find their common etiology among Sudanese children. In a case control study 150 children who were admitted to Gafar Ibn-Ouf pediatrics specialized hospital and Omdurman emergency pediatrics hospital during the period from Jun- Aug 2015 were studied. This study showed low levels of all hematological parameters in febrile seizures patients with exception of red distribution width (RDW), platelets and total iron binding capacity (TIBC) compared to their reference copartners. This evidence can be regarded as a risk factor for seizures in febrile children. The study also detected that children with low hematological levels of these parameters had a family history of febrile seizures and the consanguinity was associated with higher peak body temperature.
VL  - 3
IS  - 6
ER  -

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Author Information

Esam-eddin Bakhei Mohamed Ahmed

Department of ENT, Faculty of Medicine, Shendi University, Shendi, Sudan
Nagah Abd Elwehab Ahmed Mohamed

Department of Biochemistry, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
Faroug Bakheit Mohamed Ahmed

Department of Biochemistry, Faculty of Science and Technology, Shendi University, Shendi, Sudan
Mashair Abdelgadir

Department of Pediatrics, Faculty of Medicine, El-Neelain University, Khartoum, Sudan
Safa Ahmed Ali

Ministry of Health, Khartoum, Sudan

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APA Style

Esam-eddin Bakhei Mohamed Ahmed, Nagah Abd Elwehab Ahmed Mohamed, Faroug Bakheit Mohamed Ahmed, Mashair Abdelgadir, Safa Ahmed Ali. (2015). Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children. American Journal of Clinical and Experimental Medicine, 3(6), 332-334. https://doi.org/10.11648/j.ajcem.20150306.12

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ACS Style

Esam-eddin Bakhei Mohamed Ahmed; Nagah Abd Elwehab Ahmed Mohamed; Faroug Bakheit Mohamed Ahmed; Mashair Abdelgadir; Safa Ahmed Ali. Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children. Am. J. Clin. Exp. Med. 2015, 3(6), 332-334. doi: 10.11648/j.ajcem.20150306.12

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AMA Style

Esam-eddin Bakhei Mohamed Ahmed, Nagah Abd Elwehab Ahmed Mohamed, Faroug Bakheit Mohamed Ahmed, Mashair Abdelgadir, Safa Ahmed Ali. Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children. Am J Clin Exp Med. 2015;3(6):332-334. doi: 10.11648/j.ajcem.20150306.12

Copy | Download

@article{10.11648/j.ajcem.20150306.12,
  author = {Esam-eddin Bakhei Mohamed Ahmed and Nagah Abd Elwehab Ahmed Mohamed and Faroug Bakheit Mohamed Ahmed and Mashair Abdelgadir and Safa Ahmed Ali},
  title = {Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {3},
  number = {6},
  pages = {332-334},
  doi = {10.11648/j.ajcem.20150306.12},
  url = {https://doi.org/10.11648/j.ajcem.20150306.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20150306.12},
  abstract = {Current study aims to compare hematological parameters between children with febrile seizures and to find their common etiology among Sudanese children. In a case control study 150 children who were admitted to Gafar Ibn-Ouf pediatrics specialized hospital and Omdurman emergency pediatrics hospital during the period from Jun- Aug 2015 were studied. This study showed low levels of all hematological parameters in febrile seizures patients with exception of red distribution width (RDW), platelets and total iron binding capacity (TIBC) compared to their reference copartners. This evidence can be regarded as a risk factor for seizures in febrile children. The study also detected that children with low hematological levels of these parameters had a family history of febrile seizures and the consanguinity was associated with higher peak body temperature.},
 year = {2015}
}

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TY  - JOUR
T1  - Study of Hematological Parameters and Risk Factors for Febrile Seizure Among Sudanese Children
AU  - Esam-eddin Bakhei Mohamed Ahmed
AU  - Nagah Abd Elwehab Ahmed Mohamed
AU  - Faroug Bakheit Mohamed Ahmed
AU  - Mashair Abdelgadir
AU  - Safa Ahmed Ali
Y1  - 2015/12/07
PY  - 2015
N1  - https://doi.org/10.11648/j.ajcem.20150306.12
DO  - 10.11648/j.ajcem.20150306.12
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 332
EP  - 334
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20150306.12
AB  - Current study aims to compare hematological parameters between children with febrile seizures and to find their common etiology among Sudanese children. In a case control study 150 children who were admitted to Gafar Ibn-Ouf pediatrics specialized hospital and Omdurman emergency pediatrics hospital during the period from Jun- Aug 2015 were studied. This study showed low levels of all hematological parameters in febrile seizures patients with exception of red distribution width (RDW), platelets and total iron binding capacity (TIBC) compared to their reference copartners. This evidence can be regarded as a risk factor for seizures in febrile children. The study also detected that children with low hematological levels of these parameters had a family history of febrile seizures and the consanguinity was associated with higher peak body temperature.
VL  - 3
IS  - 6
ER  -

Copy | Download